Great Info on Joint Health
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Understanding cellular aging
Understanding cellular aging
Healthy skin looks good and feels good We all want to look and feel great for as long as possible. But if you have ever been to a school reunion, you might have noticed something interesting: Some of your classmates look older than others. Why is there such a difference in the rate at which people age? Scientists have discovered that it all starts inside our cells.
For most of us, aging means loss of muscle strength, bone density, lung capacity, and memory, and our risk for conditions such as diabetes, cardiovascular disease, dementia, and cancer all increase. When you graph the incidence of disease versus age, you notice something rather striking: Many chronic disease conditions are rare when we are young, but their incidence begins to increase around age 50. To scientists who study aging, this upsurge around age 50 suggests that there might be a common reason underlying the onset of some of the age-related diseases, and that may be cellular aging.
When we are born, we start out with a large population of healthy cells; then, ultraviolet radiation, environmental toxins, stress, and poor diet do damage to our cells. The more our cells are exposed, the more damage accumulates. It is this accumulated damage that eventually crosses a threshold that may lead to recognizable disease.1
Nutrition for your cells
What you really want to do is help your cells protect and repair themselves throughout life to help delay the onset of disease and better control the risks. One key to understanding cellular defense is knowing that cells require certain nutrients in the right amounts to be able to function normally to protect and repair themselves.2
NUTRIENTS:
EAT FRUITS AND VEGETABLES: Since only nine percent of Americans eat the recommended five servings of fruits and vegetables per day, the opportunity for improving health (and longevity) by improving diet is great.3
TAKE A MULTIVITAMIN: Deficiency of the vitamins B12, B6, C, E, niacin, and folic acid as well as iron and zinc all seem to mimic damage to DNA from radiation.4 Everyone should consider a good multivitamin to cover their basic nutritional needs.
LOAD UP ON POLYPHENOLS: Polyphenols are found in many fruits and vegetables, green tea, black tea, red wine, coffee, chocolate, olives, and extra virgin olive oil. They are plant-based nutrients that have antioxidant benefits and help protect against cellular aging.5
MUSCADINE GRAPES: These grapes, native to the United States, possess one of the highest antioxidant levels among fruits.6 They contain a high concentration of polyphenols, along with a high amount of ellagitannins and ellagic acid.7 Extracts of muscadine grape have been studied for their ability to help protect against inflammation and act as antioxidants.8,9
RESVERATROL: Studies suggest that resveratrol (a type of polyphenol) may slow cellular aging and have antiplatelet, anti-inflammatory, and cardioprotective properties.10,11
ANTHOCYANINS: This class of polyphenols, responsible for the deep red and blue coloring in fruits such as berries and grapes, possesses antioxidant, cardioprotective, and neuroprotective effects.12
While there is no way to stop the effects of aging completely, how fast you age may truly be in your control. There is a lot you can do to help slow cellular aging, and it starts with the nutrients you put in your body.
VIVIX
Every day, our cells are damaged from environmental exposure, diet and stress, which can result in the formation of free radicals. Free radicals can damage cell components like DNA and this damage can accumulate over time.
Backed by six patents, Vivix contains a proprietary, all natural blend of diverse polyphenols designed to help protect and repair DNA to Slow aging at the cellular level®. Key ingredients have been shown in laboratory studies to activate cellular defenses, neutralize free radicals and slow the development of damaging AGE proteins that can lead to cellular aging.*
Protect and repair DNA*†
40% lower rate of telomere shorteningⱡ
13x more powerful than resveratrol alone**
Available in liquigels, no refrigeration needed
Our patented extraction process concentrates and preserves the bioactive polyphenols from the world's most potent sources, including the rare muscadine grape.
Our commitment to sustainability with Vivix
To ensure eco-friendly use of the muscadine grape, Shaklee has developed a long-term partnership with a family-owned vineyard, committed to the highest standards of green and sustainable farming.
Learn more about Vivix here
Shaklee 100% Guaranteed Since 1956
1Polidori MC. Antioxidant micronutrients in the prevention of age-related diseases. J Postgrad Med. 2003 49(3):229-35.
2Møller P, Loft S. Interventions with antioxidants and nutrients in relation to oxidative DNA damage and repair. Mutat Res. 2004 551(1-2):79-89.
3Ames BN, Shigenaga MK, Hagen TM. Oxidants, antioxidants, and the degenerative diseases of aging. Proc Natl Acad Sci U S A. 1993 90(17):7915-22.
4Ames BN. Micronutrients prevent cancer and delay aging. Toxicol Lett. 1998 102-103:5-18.
5Fraga CG, Galleano M, Verstraeten SV, Oteiza PI. Basic biochemical mechanisms behind the health benefits of polyphenols. Mol Aspects Med. 2010 31(6):435-45.
6Greenspan P, Bauer JD, Pollock SH, et al. Antiinflammatory properties of the muscadine grape (Vitis rotundifolia). J Agric Food Chem. 2005 53(22):8481-4.
7Sandhu AK, Gu L. Antioxidant capacity, phenolic content, and profiling of phenolic compounds in the seeds, skin, and pulp of Vitis rotundifolia (Muscadine Grapes) As determined by HPLC-DAD-ESI-MS(n). J Agric Food Chem. 2010 58(8):4681-92.
8Gourineni V, Shay NF, Chung S, Sandhu AK, Gu L. Muscadine grape (Vitis rotundifolia) and wine phytochemicals prevented obesity-associated metabolic complications in C57BL/6J mice. J Agric Food Chem. 2012 60(31):7674-81.
9Pastrana-Bonilla E, Akoh CC, Sellappan S, Krewer G. Phenolic content and antioxidant capacity of muscadine grapes. J Agric Food Chem. 2003 51(18):5497-503.
10Wu JM, Hsieh, T-C. Resveratrol: a cardioprotective substance. Ann NY Acad Sci. 2011 1215:16-21.
11Hubbard BP, Sinclair DA. Small molecule SIRT1 activators for the treatment of aging and age-related diseases. Trends Pharmacol Sci 2014 35:146-154.
12Pojer E, Mattivi F, Johnson D, Stockley CS. The case for anthocyanin consumption to promote human health: a review. Compr Rev Food Sci Food Safety 2013 12:483-508.
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